Which drug interaction may occur when an aminoglycoside or tetracycline is given in conjunction with neuromuscular-blocking agents?
a. Deep sedation
b. Decreased effectiveness of antibiotics
c. Increased neuromuscular-blocking activity
d. Sensitivity to antibiotics and possible allergic reaction
ANS: C
Question antibiotic orders that prescribe aminoglycosides or tetracycline when neuromuscular blockers have been used. These drugs may potentiate the neuromuscular-blocking activity. This combination of medications would not cause deep sedation. Neuromuscular-blocking agents do not decrease the effectiveness of antibiotics or increase sensitivity to antibiotics.
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