The prescriber who follows the latest research regarding dosing of warfarin would consider which information prior to writing a prescription?
Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. Client's alcohol consumption
2. Amount of green, leafy vegetables the client consumes
3. CYP2D6 status
4. CYP2C9 status
5. VKORC1 status
1,2,4,5
Rationale 1: For many years, alcohol consumption has been considered when dosing warfarin.
Rationale 2: Dietary intake of green, leafy vegetables is considered when dosing warfarin.
Rationale 3: CYP2D6 status is relevant when dosing tamoxifen, not warfarin.
Rationale 4: The client's CYP2C9 status is pertinent to warfarin dosing.
Rationale 5: The client's VKORC1 status is pertinent to warfarin dosing.
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