A patient with hemophilia A is undergoing a tooth extraction at the dentist's office. As an adjunct to factor VIII, what other drug should the nurse anticipate being ordered for this patient?

a. Tranexamic acid (Cyklokapron)
b. Acetaminophen (Tylenol)
c. Desmopressin (Stimate)
d. Vitamin K


ANS: A
Antifibrinolytic drugs (eg, aminocaproic acid and tranexamic acid) can be used as adjuncts to factors VIII and IX in special situations, such as a tooth extraction.
Acetaminophen is indicated for mild pain.
Desmopressin is used as replacement therapy but is not used specifically for tooth extractions.
Vitamin K is not indicated in this situation.

Nursing

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When reviewing the studies that were included in a systematic review, a nurse is aware of the potential for publication bias. What is an implication of this phenomenon?

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