A client with hypertension has a fungal infection and has been prescribed fluconazole for the fungal infection and losartan for hypertension. The nurse would be alert for which of the following?
A) Increased risk of adverse effects of losartan
B) Increased risk of hypersensitivity reaction
C) Decreased hypotensive effect of losartan
D) Increased risk of hypoglycemia
Ans: A
Feedback:
Increased risk of antihypertensive effects and adverse reactions are associated with the concomitant use of fluconazole and losartan. Decreased hypotensive effect of losartan is seen with use of indomethacin and does not occur with the concomitant use of these drugs. Increased risk of hypoglycemia and increased risk of hypersensitivity do not occur with the concomitant use of these drugs.
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