A patient is prescribed lisinopril [Prinvil] as part of the treatment plan for heart failure. Which finding indicates the patient is experiencing the therapeutic effect of this drug?
A. + 2 edema of the lower extremities
B. Potassium level of 3.5 mEq/L
C. Crackles in the lungs are no longer heard
D. Jugular vein distention
Answer: C. Crackles in the lungs are no longer heard
Explanation: Because ACE inhibitors promote venous dilation, they provide the therapeutic effect of reducing pulmonary congestion and peripheral edema. Absence of previously heard crackles would be an indicator of effectiveness. Edema and jugular vein distention are manifestations of heart failure. A potassium level of 3.5 mEq/L is a normal value.
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