The substance present in Mycobacterium that protects it from disinfectants, including chlorinated water, is:
1. polysaccharides.
2. mycolic acid.
3. yeast.
4. acetylation.
Correct Answer: 2
Rationale 1: The substance that protects Mycobacterium is not polysaccharides.
Rationale 2: This answer is correct; the substance that protects Mycobacterium is mycolic acid.
Rationale 3: The substance that protects Mycobacterium is not yeast.
Rationale 4: The substance that protects Mycobacterium is not acetylation.
Global Rationale: The pharmacotherapy of TB differs from that of other bacterial infections because the thick mycolic acid layer surrounding the mycobacterium is resistant to penetration by anti-infectives. There is no protection from polysaccharides, yeast, or acetylation.
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