Mr. Seyer's cancer was described as Stage IV T2 N2b. Explain this terminology, which is used to describe staging for malignancies

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• The stage number I-V refers to how extensive the disease is.
- Higher numbers indicate more extensive disease, greater tumor size, and/or spread of the cancer to nearby lymph nodes and/or organs.
- In stage IV, the cancer has spread to distant tissues and organs.
• The Tumor Node Metastases (TNM) Staging System uses T, N, and M to further categorize the tumor.
- The T category describes the original tumor:
• TX means the tumor can't be measured or found.
• T0 means there is no evidence of a primary tumor.
• Tis means the tumor has not started growing into surrounding tissues.
• The numbers T1-T4 describe size and/or level of invasion into nearby structures.
- The N category describes whether or not the cancer has reached nearby lymph nodes:
• NX means nearby lymph nodes can't be measured or found.
• N0 means nearby lymph nodes do not contain cancer.
• N1-N3 describe size, location, and/or the number of lymph nodes involved.
- The M category tells whether there are distant metastases:
• MX means metastasis can't be measured or found.
• M0 means there are no known distant metastases.
• M1 means distant metastases are present.
- In stage T2 N2b, it means that cancerous cells have invaded into nearby tissues and are found in 7 or more nearby lymph nodes.

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