Which following level of evidence includes systematic reviews of multiple studies?

A) Level IV
B) Level III
C) Level II
D) Level I


D
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Systematic reviews are at the pinnacle of the hierarchy (Level I), because the strongest evidence comes from careful syntheses of multiple studies. The next highest level (Level II) includes individual randomized controlled trials (RCTs). Going down the "rungs" of the evidence hierarchy for Therapy questions results in less reliable evidence—for example, Level III evidence comes from a type of study called quasi-experiment. In-depth qualitative studies are near the bottom, in terms of evidence regarding intervention effectiveness.

Nursing

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