A newborn of 32 weeks' gestation is currently receiving nasal CPAP. The respiratory therapist recently increased the CPAP level from 8 to 10 cm H2O; the FIO2 is 0.6. On the new setting, the PaO2 is 52 mm Hg and the PaCO2 increased from 48 to 55 mm Hg

The most likely cause of this is which of the following?
a. Barotrauma
b. Alveolar overdistention
c. Ventilator-induced lung injury
d. Increased pulmonary vascular resistance


ANS: B
The rise in CO2 after the increase in the CPAP level is most likely due to pulmonary overdisten-tion, which leads to increased work of breathing. The increased WOB causes CO2 retention.

Health Professions

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