A nurse is discussing methicillin-resistant Staphylococcus aureus (MRSA) with a group of nursing students. Which statement by a student correctly identifies the basis for MRSA resis-tance?
a. "MRSA bacteria have developed PBPs with a low affinity for penicillins."
b. "MRSA bacteria produce penicillinases that render penicillin ineffective."
c. "MRSA occurs because of host resistance to penicillins."
d. "MRSA strains replicate faster than other Staphylococcus aureus strains."
A
MRSA strains have a unique mechanism of resistance, which is the production of PBPs with a low affinity for penicillins and all other beta-lactam antibiotics. MRSA resistance is not related to beta-lactamase production. MRSA resistance refers to bacterial and not host resistance. The resistance of MRSA strains is not related to speed of replication.
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