Charcot-Marie-Tooth is the most commonly inherited peripheral neuropathy, and has no known cure. Patients suffer damage to motor and sensory neurons, leading to degeneration of muscles and gradual loss of motor control.Mutation of the peripheral myelin protein 22 (PMP22) gene, which causes demyelination of peripheral neurons, is a more common cause of Charcot-Marie-Tooth disease. In which cells is the function of the PMP22 gene important for normal function?

A. Schwann cells
B. Peripheral neurons
C. Fibroblasts
D. Astrocytes
E. Oligodendrocytes


Answer: A

Biology & Microbiology

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