Prior to administering donepezil (Aricept) to a client diagnosed with Alzheimer disease, the nurse notes that the client is prescribed medications that will react with this drug. Which medications interact with donepezil (Aricept)?
Standard Text: Select all that apply.
1. Phenytoin (Dilantin)
2. Rifampin
3. Quinidine
4. Penicillin
5. Aspirin
Correct Answer: 1,2,3
Rationale 1: Decreased effects of donepezil (Aricept) will occur with concurrent administration of phenytoin (Dilantin).
Rationale 2: Decreased effects of donepezil (Aricept) will occur with concurrent administration of rifampin.
Rationale 3: Metabolism of donepezil (Aricept) may be inhibited by quinidine.
Rationale 4: Donepezil (Aricept) does not interact with penicillin.
Rationale 5: Donepezil (Aricept) does not interact with aspirin.
Global Rationale: Decreased effects of donepezil (Aricept) will occur with concurrent administration of phenytoin (Dilantin), rifampin, and quinidine. Donepezil (Aricept) does not interact with penicillin or aspirin.
You might also like to view...
The nurse is caring for a patient receiving a combination of different antineoplastic medications. The patient asks why they use so many different medications instead of just one drug
The nurse explains that a combination does what? (Select all that apply.) A) Decreases the development of cell resistance B) Increases the length of treatment C) Increases the quantity of each medication used D) Decreases the side effects of each medication E) Targets different phases of the cell cycle
Which assessment is considered abnormal when a nurse performs a neurovascular assessment on a patient in skeletal traction?
a. Delayed capillary refill b. Bilateral equal pulses c. Absence of pain and swelling d. Limb is the same color as the unaffected side
For the emergency department client who has external hemorrhage, the most appropriate way to control the bleeding is for the nurse to:
1. Apply direct manual pressure on the wound. 2. Apply a tourniquet tight enough to stop all the external bleeding. 3. Pack the wound with ice directly on the wound to cause vasoconstriction. 4. Tape ABD pads over the wound and reinforce when they become saturated.
Which condition is associated with a cyanocobalamin (B12) deficiency?
A. Pellagra B. Pernicious anemia C. Rickets D. Scurvy