The nurse is caring for a patient receiving a combination of different antineoplastic medications. The patient asks why they use so many different medications instead of just one drug

The nurse explains that a combination does what? (Select all that apply.) A) Decreases the development of cell resistance
B) Increases the length of treatment
C) Increases the quantity of each medication used
D) Decreases the side effects of each medication
E) Targets different phases of the cell cycle


A, E
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Malignant cells that remain in a dormant phase for long periods are difficult to destroy. These cells can emerge long after cancer treatment has finished—after weeks, months, or years—to begin their division and growth cycle all over again. For this reason, antineoplastic agents are often given in sequence over periods of time, in the hope that the drugs will affect the cancer cells as they emerge from dormancy or move into a new phase of the cell cycle. A combination of antineoplastic agents targeting different phases of the cell cycle is frequently most effective in treating many cancers. Combinations of drugs do not increase the length of treatment, increase the quantity of medication used, or decrease the adverse effects of the medications used.

Nursing

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