The client is going to be started on cholestyramine (Questran), 6 mg, three times daily. What instruction should the nurse provide to this client?

Question

1. Take with large amounts of fluid.
2. Take in the morning.
3. Take with food.
4. Take without food.

Answer 1

1

Rationale 1:Cholestyramine (Questran) is a bile acidbinding drug that must be taken with large amounts of fluid. It binds to the cholesterol in the intestine and is eliminated in the feces.
Rationale 2:Cholestyramine (Questran) is a bile acidbinding drug that must be taken 1 hour after or 4 hours before other medications are taken.
Rationale 3:Cholestyramine(Questran) is a bile acidbinding drug that must be taken 1 hour after or 4 hours before other medications are taken. It binds to the cholesterol in the intestine and is eliminated in the feces.
Rationale 4:Cholestyramine(Questran) is a bile acidbinding drug that must be taken 1 hour after or 4 hours before other medications are taken.

Global Rationale: Cholestyramine (Questran) is a bile acidbinding drug that contains a high concentration of cholesterol and is secreted by the liver to aid in the digestion of fats in the small intestine. Once bound in the intestine, the cholesterol in the bile acids is eliminated in the feces. It is prescribed three times a day and taken with large amounts of water.