What is the difference between a gene knockout and a gene knockdown?
What will be an ideal response?
A gene knockout is when researchers replace the normal gene with a defective one so that no
functional protein product can be made from that gene. A gene knockdown is when researchers
decrease the amount of expression from a gene by using a technique such as RNA interference. Both
are used to assess the phenotype of changing a gene’s function in the cell.
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Using the NeoR/Tk system of introducing gene replacements into mice (as described in the text), which of the following would identify those mouse cells that were the result of homologous recombination?
A. NeoR only B. Tk only C. NeoR and Tk D. Neither NeoR or Tk
The portion of a mushroom that you typically eat is
a. the fruiting body. b. the reproductive structure. c. the chytrid sac. d. both the fruiting body and the reproductive structure.
When membrane lipids are extracted from cells and used to prepare artificial lipid bilayers, cholesterol and sphingolipids tend to self-assemble into ________ that are more gelated and highly ordered than surrounding regions consisting primarily of _________.
a) microdomains, integral proteins b) microdomains, phosphoglycerides c) liquid crystals, microdomains d) liquid crystals, phosphoglycerides e) macrodomains, phosphoglycerides
The offspring of a cross between two individuals that breed true for different forms of a trait are __________.
Fill in the blank(s) with the appropriate word(s).