Explain how stomach acidity can affect drug absorption


?Some drugs are absorbed better in an acidic environment, whereas others are absorbed better under alkaline conditions. For example, reduced stomach acidity (due to secretory disorders or antacid medications) may reduce the absorption of ketoconazole (Nizoral, an antifungal medication) and atazanavir (an antiretroviral medication), but increase the absorption of digoxin (Lanoxin, which treats heart failure) and alendronate (Fosamax, which treats osteoporosis). Some drugs can be damaged by acid and are available in coated forms that resist the stomach's acidity.

Nutritional Science

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Alcohol absorption occurs in the ________.

A. stomach B. esophagus C. small intestine D. stomach and small intestine

Nutritional Science

Unlike B vitamins, vitamin C is:

A) not a coenzyme. B) fat-soluble. C) not present in plant-based foods. D) is toxic in high doses.

Nutritional Science

Monica has been trying to lose weight for about a year. Throughout the past year she has educated herself on the guidelines of good nutrition and exercise. Despite knowing that she needs to change her lifestyle, she is frustrated with her inability to lose weight and wants to "jumpstart" her weight loss. She is trying to lose 5-10 lbs. as soon as possible because she feels that gradual changes

are emotional downers and she is unable to commit to gradual change. She ends up over eating, eating out of balance, and ceasing to exercise. Her most recent diet is as follows: day 1: fruits only, day 2: vegetables only, day 3: fruits and vegetables only, day 4: 6 bananas and milk, days 5 and 6: tomatoes only, day 7: eat whatever you want. In addition to the diet Monica is exercising daily for 1-2 hours. What type of diet would be helpful for Monica to follow to facilitate weight loss? A) A high-carbohydrate, low-fat, low-protein diet B) A diet that provides ample protein and plenty of complex carbohydrates and is low in saturated fat and refined carbohydrates C) A high-protein, low-carbohydrate, high-fat diet D) A diet similar to the one she is currently following

Nutritional Science

Briefly describe the process of restriction and reintroduction of dairy products to clients with lactose malabsorption.

What will be an ideal response?

Nutritional Science