A patient who is being treated with topical mafenide acetate for third-degree burns is demonstrating facial and neck edema. What does the nurse realize is the most likely reason?
1. The patient is developing hypersensitivity to the medication.
2. The patient is reacting positively to the medication.
3. The patient needs an increase in dosage of the medication.
4. The patient is not responding to the medication.
Correct Answer: 1
Approximately 3%–5% of patients develop hypersensitivity to mafenide acetate, which can manifest as facial edema. Facial and neck edema is considered an adverse reaction. The information presented is inadequate to assess whether the dosage should be increased.
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