Discuss the theories of aging and how caloric restriction may serve to prolong life


Theories of aging can be examined from two perspectives: (1) programmed aging theories and (2) "wear-and-tear" theories. Programmed aging theories include Hayflick's Theory of Limited Cell Replication, and the Molecular Clock Theory. Wear-and-Tear Theories of Aging include the Free-Radical or Oxidative Stress Theory, and the Rate of Living Theory.
Studies have shown that caloric restriction, especially in midlife, results in longer life spans. One mechanism might be that it leads to changes in cell signaling pathways that induce metabolic reprogramming and subsequent life extension.

Nutritional Science

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Blood levels of very low-density lipoproteins (VLDLs) are decreased by

A. exercise. B. simple sugars. C. extra Calories. D. dietary cholesterol.

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Rosa, age 84, is unable to care for herself at home. She had a stroke 6 months ago and is in the nursing home. She requires total care by the nursing staff. ?

Rosa has developed anemia. State causes and dietary recommendations.

Nutritional Science