You have a patient in your office who has the autoimmune disease systemic lupus erythematosus, which is being successfully treated using immunosuppressive drugs. Generally you recommend a yearly flu shot to your patients, which is available either in an injected, inactivated form or as a live, attenuated virus nasal spray. For this patient, what detail should you consider?

A. You should wait about six weeks to vaccinate, until the lupus passes through the patient and she is well.
B. The injected, inactivated vaccine would be a better choice than the live attenuated nasal spray vaccine, since the patient is on immunosuppressive drugs.
C. Having lupus demonstrates that the patient does not have a functional immune system, and therefore it would be pointless to vaccinate.
D. Since she has an autoimmune disease, the patient is likely to be allergic to chicken eggs, and should not get the vaccine.


Answer: B

Biology & Microbiology

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