The highly repetitive minisatellite DNA regions of the genome are highly polymorphic in the number of copies of the individual repeats among different individuals

They are often used for "fingerprinting" individuals for forensic analysis. Describe how the process of unequal crossing over alters the copy number of these repeats.
What will be an ideal response?


Ans: A recombination event occurs between two copies of the repeat on homologous chromosomes that are not located at the same position in the chromosome (the repeats are not in register with one another). This results in unequal crossing over (also called nonreciprocal recombination), resulting in an increase in the number of copies of the repeat in one chromosome and a decrease in the copy number in the other.

Biology & Microbiology

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