Contraindications for beginning fibrinolytic therapy include which of the following? Select

all that apply.

a. Currently on Coumadin with an INR of 2.4
b. Major surgery in the last 14 days
c. Systolic BP of 150
d. Platelet count of less than 100,000
e. Blood glucose of less than 50 mg/dL
f. History of myocardial infarction 1 year ago
g. Improving neurologic status


a, b, d, e, f, g
For a patient to qualify for fibrinolytic therapy, the neurologic signs should not be clearing
spontaneously. There should be no history of head trauma, myocardial infarction, or prior stroke
in the past 3 months or major surgery in past 14 days. The patient's platelet count must be greater
than 100,000 and the blood glucose level greater than 50 mg/dL (2.7 mmol). The systolic BP needs
to be less than 185 and the diastolic BP less than 110 . The patient should not be taking an oral
anticoagulant; if so, the INR must be less than 1.7.

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