Discuss the gene variant associated with folate status and its importance to preconceptional women
Some individuals have an increased need for folate due to specific gene variants involved in folate metabolism. These gene variants can impair the conversion of folate to its active form and increase folate requirement. One of the best-studied and most common gene variants affects 5, 10-methylenetetrahydrofolate reductase (MTHFR) activity. This enzyme is responsible for production of the major circulating form of folate used by the body. The C677T allele of the gene that encodes for MTHFR produces an enzyme that has reduced activity. Women with this gene variant are at increased risk of having an NTD-affected newborn.
You might also like to view...
Studies suggest that an increase in potassium intake can:
a. lower blood triglycerides. b. lower blood pressure. c. raise high-density lipoprotein (HDL) levels. d. raise blood sugar levels.
A gram of protein contains ________ calories
A) 10 B) 4 C) 3 D) 5
Nutritional therapy for hepatitis includes:
a. high protein, high carbohydrate, moderate fat, high calories b. high protein, low carbohydrate, low fat, moderate calories c. low protein, high carbohydrate, low fat, high calories d. low protein, high carbohydrate, low fat, low calories
What is the name of the vitamin A compound that is active in the visual response?
A) ?opsin B) ?keratin C) ?retinal D) ?carotene