Microsatellites are short sequences of DNA that consist of several two- or three- nucleotide motifs repeated in tandem (e.g., AATAATAAT or GAGAGAGAGAGA). Each allele consists of a different number of repeats. Microsatellites are typically not under selection, and they are inherited through Mendelian inheritance. Given this information, which of the following questions might you answer with the use of microsatellites?
A) whether a gene is dominant or recessive
B) whether your child will be blonde- or brown-haired
C) whether two puppies were sired by the same father
D) whether your canary died of a viral or bacterial infection
E) whether a human fetus is male or female
Ans: C) whether two puppies were sired by the same father
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When processing a culture swab in the diagnostic laboratory the microbiologist should:
a. inoculate the media prior to making the direct smear. b. roll the swab back and forth on the slide making sure to transfer organisms. c. prepare the smear by rubbing the slide with one side of the swab and utilize the opposite slide to inoculate media. d. cancel the direct Gram stain and only set up the media. Request a second swab for the direct smear.
Which event in inflammation aids in white blood cells migrating from the blood vessel to the site?
a. Arterioles widen. b. Blood flow produces heat in the area. c. Capillary permeability is increased. d. Complement is activated. e. Phagocytes engulf complement coated bacteria.
The different globin genes in each cluster are sequentially expressed in tightly controlled patterns during the various stages of prenatal and adult development
What gene structure helps regulate globin gene transcription by controlling both the timing and the starting point for transcribing DNA into mRNA?
"Immediate early genes" such as myc can best be thought of as genes that
a) Are only expressed in the absence of growth factor (GF) stimulation b) Become permanently switched off during tumorigenesis c) Code for GF receptors such as RTKs d) Represent the first wave of expression following GF stimulation