A nurse understands that the pathophysiology of Parkinson's Disease includes which of the fol-lowing? (Select all that apply.)
a. A deficiency of the neurotransmitter do-pamine
b. An inability of the neurons to absorb do-pamine
c. A reduction of dopamine receptors
d. An accumulation of Lewy Bodies, espe-cially in the basal ganglia
e. The presence of neurofibrillary tangles and amyloid plaques in the brain
ANS: A, C, D
Parkinson's Disease is the result of a deficiency of the neurotransmitter dopamine, a reduction of dopamine receptors, and the accumulation of Lewy Bodies, especially in the basal ganglia. The presence of neurofibrillary tangles and amyloid plaques in the brain is seen in Alzheimer's Dis-ease.
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