A genetic test result returns noting that the specimen (client) has inclusion bodies in the sample. The health care provider can associate this result with the development of which pathologic disease process? Select all that apply
A) Alzheimer disease
B) Parkinson disease
C) Myasthenia gravis
D) Multiple myeloma
Ans: A, B
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Disruption of chaperoning mechanisms causes intracellular molecules to become denatured and insoluble. These denatured proteins tend to stick to one another, precipitate, and form inclusion bodies. The development of inclusion bodies is a common pathologic process in Parkinson, Alzheimer, and Huntington diseases.
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