Which physiologic findings are seen with respect to gallbladder function that might lead to the development of gallstones during pregnancy?
a. Decrease in alkaline phosphatase levels compared with nonpregnant women
b. Increase in albumin and total protein as a result of hemodilution
c. Hypertonicity of gallbladder tissue
d. Prolonged emptying time
ANS: D
Prolonged emptying time is seen during pregnancy and may lead to the development of gallstones. In pregnancy, there is a twofold to fourfold time increase in alkaline phosphatase levels as compared with those in nonpregnant woman. During pregnancy, a decrease in albumin level and total protein are seen as a result of hemodilution. Gallbladder tissue becomes hypotonic during pregnancy.
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