The parents of a child diagnosed with cystic fibrosis (CF) consult the nurse, stating they want to have more children but are worried about subsequent children also having the disease. Which information does the nurse provide the parents?
A.
"Each child has a 25% chance of inheriting the disease."
B.
"This disease is rare, so other children should not be affected."
C.
"Unfortunately, there is no way to predict if they will have it."
D.
"You should have genetic testing to see who the carrier is."
ANS: A
Cystic fibrosis is an inherited autosomal recessive disorder. When both parents carry the defective gene, each child has a 25% chance of inheriting the defective gene from both parents and manifesting the disease. It is a common disorder, especially in Caucasians, affecting 1 in 3,000 live births.
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