A patient who has recently started therapy on an HMG-COA reductase inhibitor drug asks the nurse, "How long will it take until I see an effect on my LDL cholesterol?" The nurse correctly states
a. "At least 6 months is required to see a change."
b. "A reduction usually is seen within 2 weeks."
c. "Blood levels normalize immediately when the drug is started."
d. "Cholesterol will not be affected, but triglycerides will fall within the first week."
ANS: B
Reductions in LDL cholesterol are significant within 2 weeks and maximal within 4 to 6 weeks.
It does not take 6 months too see a change.
The blood level of LDL cholesterol is not reduced immediately upon starting the drug; a reduction is seen within 2 weeks.
Blood cholesterol is affected, specifically LDL cholesterol, not triglycerides.
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