The nurse is providing care to a client with diabetes who is receiving sulfonamides. The nurse counsels the client about the increased risk of hypoglycemia, especially if the client is taking which of the following medications? Select all that apply
A) Tolbutamide (Orinase)
B) Lisinopril (Prinivil)
C) Simvastatin (Zocor)
D) Losartan (Cozaar)
E) Chlorpropamide (Diabinese)
Ans: A, E
Feedback:
Sulfonamides may inhibit the hepatic metabolism of the oral hypoglycemic drugs tolbutamide (Orinase) and chlorpropamide (Diabinese). Elderly clients may be especially sensitive to this reaction. Lisinopril, simvastatin, and losartan are used for cardiac conditions.
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