The nurse is planning care for patients with hypertension. Which ethnic group should the nurse understand is most sensitive to the effects of the beta blocker propranolol (Inderal)?
a. Chinese
b. Koreans
c. African Americans
d. Japanese Americans
ANS: C
Hypertension among African Americans is usually caused by increased renin activity resulting in greater sodium and fluid retention. African Americans respond better to diuretics such as furosemide (Lasix) than to beta blockers such as propranolol (Inderal). A. Chinese people are more sensitive than Caucasians to the effects of propranolol on heart rate and blood pressure, requiring only half the blood level of European Americans to achieve a therapeutic effect. Propranolol is eliminated from the bodies of many Chinese people at double the rate of European Americans. They are more likely to suffer fatigue as a side effect. The nurse must carefully monitor the Chinese patient for therapeutic and side effects. B. D. There is no information to suggest that individuals of Korean or Japanese descent cannot take propranolol (Inderal).
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