When planning care for a client with MODS secondary to septic shock, the nurse suggests which of the following to the provider, as evidence shows a reduction in mortality?
1. Recombinant activated protein C (xigris)
2. Heparin
3. Packed red blood cell transfusion
4. Dobutamine (Dobutrex)
Recombinant activated protein C (xigris)
Rationale: Recombinant activated protein C (xigris) is indicated for clients with a high risk of death, such as organ failure. Heparin is not typically used in the treatment of septic shock. Packed red blood cell transfusions are used to increase the oxygen-carrying capacity of the blood, such as after hemorrhage. Blood transfusions do not improve survival in septic shock. Dobutamine is added in septic shock to improve cardiac output, but has not been shown to improve survival.
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