Which of the following is not true of the nucleolytic proofreading reaction of bacterial RNA polymerase?

A. Water is the nucleophile.
B. It occurs when the enzyme backtracks after incorporating a mismatched base.
C. rNTP is the product.
D. It involves the melting of several RNA-DNA base pairs.
E. All of the choices given are true.


C

Biology & Microbiology

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