Which statement best describes drug efficacy/toxicity in pediatric patients?
A) Drug requirements for infants have been extensively studied.
B) Drug dosage is altered by age and weight in children.
C) Children always need smaller doses of medication than adults.
D) Infants and children are not at risk for drug toxicity if the dosage is correct.
B
Feedback:
All aspects of pediatric drug therapy must be guided by the child's age, weight, and level of growth and development. Drugs are generally studied using healthy young men and are never studied in infants because they are not old enough to give consent for themselves. Drug dosages are very specific and a big child may weigh more than an adult and require a larger dose. Even when medications are given accurately, adverse effects can occur.
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