Describe testing of genotype and phenotype assays for HIV mutations


In addition to adequate testing for the presence and levels of HIV in the blood, testing for viral mutations through genotype and phenotype assays can assist the process of choosing the most potentially effective therapies. A genotype assay is used to identify points in the DNA sequence of the virus genome that may be mutated and cause resistance to treatment. Phenotype assays are used to determine viral susceptibility to a particular drug. In some cases, genotype predictions of drug resistance and phenotype testing for resistance may show different results or discordance. The prediction of virus susceptibility based on genotype and phenotype testing may assist in the effective use of medications and help to limit the exposure to medications and their associated toxicities when resistance is likely.

Nutritional Science

You might also like to view...

Which of the following constituents in cajuput is an expectorant:

A. Eucalyptol B. Limonene C. a-pinene D. Cedrene

Nutritional Science

One of the cardinal rules of deep-fat frying is to maintain temperature of the oil as well as the food

Indicate whether the statement is true or false

Nutritional Science

If creatine phosphate is nearly depleted in skeletal muscle by high-intensity exercise, how is it rephosphorylated?

a. By consuming creatine as a dietary supplement b. By consuming ATP as a dietary supplement c. From ATP generated anaerobically by glycolysis d. From ATP generated aerobically by oxidative phosphorylation

Nutritional Science

Which athlete would likely use protein as an energy source during competition?

a. Marathon runner b. 800 meter runner c. Body builder d. Rower

Nutritional Science