A client has been prescribed denosumab (Prolia). What medication education should the nurse provide?
1. "I will give your medication in the form of an injection."
2. "You may feel more fatigued than usual when taking this drug."
3. "Be certain to keep your appointments for follow-up."
4. "Do not take any kind of calcium supplement or vitamin D supplement while taking this drug."
5. "We must monitor your cholesterol while you are taking this drug."
Correct Answer: 1,2,3,5
Rationale 1: Denosumab is given subcutaneously.
Rationale 2: An adverse reaction of this drug is fatigue.
Rationale 3: This drug can cause severe hypocalcemia, so it is important to monitor lab values.
Rationale 4: Calcium and vitamin D supplementation may be necessary to keep serum calcium at normal level.
Rationale 5: This drug may result in hypercholesterolemia.
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1. Contract the buttock muscles five times every two hours. 2. Increase fat in the diet to provide a protective coating over the boney prominences. 3. Do wheelchair push-ups every 15 to 30 minutes. 4. Avoid use of sheepskin as it prevents air from reaching the area.
A patient is receiving slow continuous ultrafiltration to treat an acute kidney injury. Which nursing assessment will this treatment specifically require?
1. Electrolyte levels 2. White blood cell count 3. Appetite 4. Urine output
Factors that affect gastric drug absorption include:
1. Liver enzyme activity 2. Protein-binding properties of the drug molecule 3. Lipid solubility of the drug 4. Ability to chew and swallow
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