A nurse is caring for a 15-year-old who has just been diagnosed with non-Hodgkin lymphoma. Which of the following should the nurse include in teaching the parents about this lymphoma? Select all that apply.
1. The malignancy originates in the lymphoid system.
2. The presence of Reed-Sternberg cells in the biopsy is considered diagnostic.
3. Mediastinal involvement is typical.
4. The disease is diffuse rather than nodular.
5. Treatment includes chemotherapy and radiation.
1, 3, 4, 5.
rationale for each:
1. Non-Hodgkin disease originates in the lymphoid system.
2. Reed-Sternberg cells are diagnostic for Hodgkin disease and are not seen in non-Hodgkin lymphoma. Reed-Sternberg cells arise from "B" cells and are large, multinucleated cells.
3. Mediastinal involvement is typical.
4. The disease is diffuse rather than nodular.
5. Treatment includes chemotherapy and radiation.
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