What form of diabetes is characterized by destruction of pancreatic beta cells, resulting in insulin deficiency?
a. Type 1 diabetes
b. Type 2 diabetes
c. Gestational diabetes
d. Maturity-onset diabetes of the young (MODY)
ANS: A
Type 1 diabetes is characterized by the destruction of the pancreatic beta cells, which leads to absolute insulin deficiency. Type 2 diabetes results usually from insulin resistance. The pancreatic beta cells are not destroyed in gestational diabetes. MODY is an autosomal dominant monogenetic defect in beta cell function that is characterized by impaired insulin secretion with minimum or no defects in insulin action.
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