A 7-year-old boy fell off a wood pile while playing. He has been admitted to the intensive care unit with multiple broken bones and internal bleeding. What should the nurse know about drug therapy in this type of patient?
A) Adverse effects may be decreased.
B) Therapeutic effects may be increased.
C) Pharmacodynamics may be altered.
D) Pharmacokinetics remain the same.
C
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The child's developmental age will influence pharmacokinetics and pharmacodynamics; the immature liver may not metabolize drugs in the same way and the kidneys may not work as efficiently as those of an adult. Adverse effects might be increased and therapeutic effects may be decreased.
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