What is the action of a drug antagonist?
1. It facilitates cell action.
2. It does not bind with receptors.
3. It blocks the actions of an agonist.
4. It has no therapeutic benefit.
Correct Answer: 3
Rationale 1: Agonists facilitate drug action; antagonists block the effects of agonists.
Rationale 2: Many therapeutically useful drugs act by blocking receptors (e.g., beta-adrenergic blockers, antihistamines).
Rationale 3: Blocks the actions of an agonist is the definition of an antagonist.
Rationale 4: Many therapeutically useful drugs act by blocking receptors (e.g., beta-adrenergic blockers, antihistamines).
Global Rationale: Blocks the actions of an agonist is the definition of an antagonist. An agonist facilitates drug action. Many therapeutically useful drugs act by blocking receptors (e.g., beta-adrenergic blockers, antihistamines); therefore, not biding with receptors and it has no therapeutic effect are both incorrect.
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