What is the function of the human NHEJ system? What is the result of mutations of genes in this system?

What will be an ideal response?


Ans: The nonhomologous end-joining (NHEJ) system is responsible for the repair of double-strand breaks in chromosomes, specifically by recognizing broken ends and ligating them together. Mutations in genes of this system can result in several human diseases that stem from the inability to repair these breaks, leading to mutations and a high susceptibility to cancer.

Biology & Microbiology

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Chemical inhibitors of hormone synthesis or signaling are powerful tools that yield invaluable information about hormone function.  Triadimefon, propiconazole, and spironolactone are just a few of the compounds identified to inhibit the function of brassinosteroids (BR). Which of the following are probable physiological effects due to the inhibition of BR? Check all that apply.  

_____  reduced mitotic activity _____  rapid aging _____  reduced xylem and phloem differentiation _____  increased stem length Clarify Question · What is the key concept addressed by the question? · What type of thinking is required? · What key words does the question contain and what do they mean?   Gather Content · What do you already know about brassinosteroids? How does it relate to the question?   Consider Possibilities   · What other information is related to the question? Which information is most useful?   Choose Answer · Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer? Reflect on Process · Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?

Biology & Microbiology

In the figure above, the viral DNA in the lysogenic pathway ____

is no longer present

a. has been destroyed by host bacterial enzymes b. is integrated into the bacterial chromosome c. has been copied and changed into bacterial DNA d. is no longer present

e. has been transcribed into RNA

Biology & Microbiology

The energy necessary to drive the bacteriorhodopsin proton pump that creates the proton gradient needed for ATP synthesis is generated by

A) a Na+ electrochemical gradient across the membrane. B) a H+ concentration gradient across the membrane. C) a membrane potential of 100 mV across the membrane. D) ATP hydrolysis by ATP synthase. E) retinal absorption of light energy.

Biology & Microbiology

You find a new organic molecule that is water soluble and contains the elements carbon, nitrogen, hydrogen, and oxygen. It is probably a 

A. protein. B. fat. C. carbohydrate. D. phospholipid.

Biology & Microbiology