A nurse is discussing the administration of an intravenous infusion of rituximab (Rituxan) with a nursing student. Which statement by the student indicates a need for further education about the care of a patient receiving this drug?
a. "Angioedema and hypersensitivity may occur, but they are usually self-limiting and mild."
b. "I should be prepared to administer epi-nephrine, glucocorticoids, and oxygen if needed."
c. "I will administer an antihistamine and acetaminophen before beginning the infu-sion."
d. "I will monitor this patient's blood pres-sure, respiratory rate, and oxygen satura-tion closely."
A
Rituximab can cause severe infusion-related hypersensitivity reactions. Nurses should be pre-pared to administer epinephrine, steroids, and O2 if needed. Antihistamines and acetaminophen are given before infusion. Close monitoring of vital signs and oxygenation are indicated.
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