A patient tells a nurse that antihistamines help relieve cold symptoms and wants to know why they are not recommended or prescribed for this purpose. The nurse tells the patient that antihistamines provide relief from some cold symptoms by:
a. blocking H1 receptors in nasal passages.
b. blocking muscarinic receptors in the nose.
c. reducing secretions at H2 receptor sites.
d. having sedative effects, which help patients rest and sleep.
ANS: B
Histamine does not mediate cold symptoms, so antihistamines do not provide relief through H1 blockade. Their anticholinergic effects at muscarinic receptor sites can moderately reduce rhinorrhea, so some patients may experience some relief of this symptom. H1-receptor sites do not play a role in cold symptoms. H2-receptor sites do not play a role in cold symptoms. Sedative side effects do not alleviate cold symptoms.
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