The nurse is caring for four patients. Which patient would have the highest risk for hepatotoxicity from dantrolene (Dantrium)?
A) An 87-year-old man who is taking a cardiac glycosideh
B) A 32-year-old man who is taking an antipsychotic drug
C) A 65-year-old woman who is on hormone replacement therapy
D) A 48-year-old woman who is taking an antihypertensive agent
C
Feedback:
If dantrolene is combined with estrogen, the incidence of hepatocellular toxicity is increased. This combination should be avoided. Nothing indicates that patients taking a cardiac glycoside, an antipsychotic drug, and an antihypertensive would have serious adverse effects when combined with dantrolene therapy.
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