Which of the following statements regarding hypersensitivity are true? (Check all that apply.)
_____ The acceptance of self cells is known as immunological tolerance.
_____ Allergies are caused by IgG secretion in response to antigens.
_____ Autoreactive B cells produce autoantibodies causing inflammation.
_____ Itchy welts or hives could be called a local anaphylaxis.
_____ Delayed hypersensitivity is mediated by TH cells and macrophages.
__X__ The acceptance of self cells is known as immunological tolerance.
_____ Allergies are caused by IgG secretion in response to antigens.
__X__ Autoreactive B cells produce autoantibodies causing inflammation.
__X__ Itchy welts or hives could be called a local anaphylaxis.
__X__ Delayed hypersensitivity is mediated by TH cells and macrophages.
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Which of the following statements is true regarding T cell receptors? Select all correct
A. They recognize antigen-MHC complexes. B. They contain variable and constant regions. C. They are composed of two heavy (H) chains and two light (L) chains. D. They are formed by the rearrangement of V, J, C, and D gene segments. E. They can be found in the bloodstream independent of T cells.
Responsible scientists provide ____ to back up their statements
a. hypotheses b. predictions c. evidence d. controls e. problems
Which one of the following causes transmembrane channels in target cells?
A) granzymes B) hapten C) IL-1 D) IL-2 E) perforin
Dosage compensation in mammals typically involves the random inactivation of one of the two X chromosomes relatively early in development. Such X chromosome inactivation often leads to phenotypic mosaicism. Assume that black fur in cats is due to the
X-linked recessive gene b, whereas its dominant allele B produces yellow fur. A Bb heterozygote is a mosaic called "tortoise shell" or "calico." A mating between a black male and a calico female occurred. Give the phenotypes of the offspring. A) all black regardless of sex B) calico females, black females, yellow makes, and black males C) calico females and yellow males D) all calico regardless of sex E) calico females, yellow females, black males, and yellow males