In what way can loss of heterozygosity lead to cancer?

What will be an ideal response?


Loss of heterozygosity occurs when a cancer-producing gene that exists in the heterozygous state becomes exposed through deletion, mutation, recombination, uniparental disomy, or chromosomal aberration. Such a gene now is either homozygous or hemizygous.

Biology & Microbiology

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The synthesis of ATP from ADP and Pi is a(n) _____ reaction with a ____ G

A. exergonic; positive B. endergonic; negative C. exergonic; negative D. endergonic; positive E. reversible; 0

Biology & Microbiology

As plant cells rely on energy obtained directly from the sun to carry out any cellular processes, sugars are only used as backup energy sources for plants on cloudy days.

a. true b. false

Biology & Microbiology

Phosphatases are a family of enzymes that specifically remove phosphate groups from proteins that were added by protein kinases. Vanadate is an inhibitor of phosphatases in eukaryotic cells

What effect would vanadate have on the response of cells to signals received by receptor kinases? A. The response of the cell would last longer than it normally would. B. The response of the cell would be shorter than it normally would. C. The signal would still bind the receptor, so there would be no effect.

Biology & Microbiology

A scientist is studying a population of feral cats in his city. After ten years, he notes that—for the population of feral cats he is studying—(K–N)/K = 0

Based on this information, what can he deduce about the logistic growth curve for the population at this point in time (recall Figure 46.5)? A. The curve resembles an exponential growth curve. B. The curve is at its inflection point (i.e., the rate of growth has started to slow). C. The curve has plateaued at K. D. The curve is at its steepest point.

Biology & Microbiology