Which of the following is not a characteristic of an autosomal recessive disorder pedigree?
A. Affected children can have unaffected parents.
B. Both males and females are affected with equal frequency.
C. Two affected parents will always have affected children.
D. Affected individuals with homozygous unaffected mates will have unaffected children.
E. Heterozygotes have an affected phenotype.
Answer: E
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