Angiotensin receptor blockers (ARBs) work in the body to lower blood pressure by which mechanism of action?
1. Inhibiting the stimulation of aldosterone secretion
2. Blocking the conversion of angiotensin I to angiotensin II
3. Blocking AT1 receptors, which prevent angiotensin from raising blood pressure
4. Blocking the formation of renin in the RAAS system
Correct Answer: 3
Rationale 1: ARBs do not block the stimulation of aldosterone secretion. Aldosterone antagonist drugs work in this way.
Rationale 2: ARBs do not prevent the conversion of angiotensin I to angiotensin II. ACE inhibitor drugs work at this stage of the pathway.
Rationale 3: By blocking the AT1 receptors, the ARBs prevent angiotensin from raising blood pressure.
Rationale 4: ARBs do not block the formation of renin in the RAAS system.
Global Rationale: By blocking the AT1 receptors, the ARBs prevent angiotensin from raising blood pressure. ARBs do not block the stimulation of aldosterone secretion. Aldosterone antagonist drugs work in this way. ARBs do not prevent the conversion of angiotensin I to angiotensin II. ACE inhibitor drugs work at this stage of the pathway. ARBs do not block the formation of renin in the RAAS system.
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Which option provides information that allows an individual to identify the patient's affective state?
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