Both people in a married couple carry the recessive gene for cystic fibrosis. When asked about the incidence of any children developing the disorder, what should the nurse respond?

A) "There is no chance.".
B) "There is a 1 in 4 chance.".
C) "There is a 2 in 4 chance.".
D) "There is a 3 in 4 chance.".


B
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In autosomal recessive inheritance, the disease will not occur unless both parents have recessive genes for the disorder. There is a 25% chance a child born to the couple will be disease and carrier free; a 50% chance the child will be, like the parents, free of disease but carrying the unexpressed disease gene; and a 25% chance the child will have the disease, or a 1 in 4 chance. With the recessive gene carried by both parents, the chances of children developing the disease are not 2 in 4, 3 in 4, or 0 in 4.

Nursing

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