Which of the following will NOT result in a proto-oncogene's conversion into an oncogene?

a. A mutation in the proto-oncogene's promoter that increases transcription of the gene.
b. A mutation in the coding sequence of a protein that renders a protein abnormally active.
c. An alteration to the p53 coding sequence rendering the p53 protein inactive.
d. An introduction of new DNA sequences to a chromosome that alters the regulation of the
cell cycle.
e. The translocation of a proto-oncogene to a location in the cell and under the control of a
more active promoter than present in the original location.


C

Biology & Microbiology

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