For which symptoms should the nurse teach the client to monitor when taking doxazosin (Cardura)?
1. Dizziness and headache
2. Difficulty in breathing
3. Decreased urinary frequency
4. Constipation
Correct Answer: 1
Rationale 1: The most common side effects of doxazosin (Cardura) include dizziness, drowsiness, fatigue, and weakness. Also, first-dose syncope can occur 30 to 90 minutes following the initial dose, so the nurse should teach the client to be cautious.
Rationale 2: Doxazosin (Cardura) has no effect on the bronchi or the bronchioles, since the receptors in the bronchus are beta2 receptors.
Rationale 3: Doxazosin (Cardura) causes relaxation of smooth muscle of the bladder and prostate, causing increased urinary frequency, not decreased urinary frequency.
Rationale 4: Doxazosin (Cardura) is a selective alpha1-adrenergic antagonist that causes a rapid decrease in peripheral resistance that reduces blood pressure. It does not have any effect on the smooth muscle of the GI tract.
Global Rationale: The most common side effects of doxazosin (Cardura) include dizziness, drowsiness, fatigue, and weakness. Also, first-dose syncope can occur 30 to 90 minutes following the initial dose, so the nurse should teach the client to be cautious. Doxazosin (Cardura) has no effect on the bronchi or the bronchioles, since the receptors in the bronchus are beta2 receptors; it causes relaxation of smooth muscle of the bladder and prostate, causing increased urinary frequency, not decreased urinary frequency; and it is a selective alpha1-adrenergic antagonist that causes a rapid decrease in peripheral resistance that reduces blood pressure. It does not have any effect on the smooth muscle of the GI tract.
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